[PDF][PDF] Bone markers

D Konukoglu - Int J Med Biochem, 2019 - jag.journalagent.com
… tropocollagen are the Ntelopeptide and C-telopeptide regions. Cross-links … that monoclonal
antibodies against sclerostin decrease bone resorption … Serum CTX is always ß-isomerized. …

Markers of bone and cartilage turnover

HW Woitge, MJ Seibel - Experimental and Clinical …, 2017 - thieme-connect.com
… , whereas collagen degradation products may … uses two monoclonal antibodies recognising
dipeptides that contain a crosslink and two β-isomerised peptides within the same sequence

[PDF][PDF] Biosensors for the measurement of C-terminal telopeptide of type I Collagen (CTX-I)

N Afsarimanesh, SC Mukhopadhyay… - J. Osteoporos. Phys …, 2017 - researchgate.net
… The tube surface was coated with the eight amino acid peptide … using the developed FMGC,
PEG4-EKGPDP and antibodies … a monoclonal antibody to urinary degradation products from …

Bone turnover markers: basic biology to clinical applications

M Schini, T Vilaca, F Gossiel, S Salam… - Endocrine …, 2023 - academic.oup.com
… In the last 20 years, much experience has been gained in measurement and … used resorption
markers (serum C-telopeptides of type I collagen, urinary N-telopeptides of type I collagen, …

… ) as a Sampling Technique for β Isomerized Carboxy Terminal Telopeptide (β-CTX) and Type 1 Procollagen Amino Terminal Propeptide (P1NP) Determination Using …

C Washbourne - 2022 - ueaeprints.uea.ac.uk
… on the collagen formation and breakdown products 83 for this … and 325 providing the
reaction environment with the co-… using two monoclonal antibodies against the linear β‑8 342 …

The use of type I collagen cross-linked C-telopeptide (CTX-1) as a biomarker associated with the formation of periprosthetic ossifications following total hip joint …

P Łęgosz, Ł Pulik, P Stępiński… - Annals of Clinical & …, 2018 - Assoc Clin Scientists
… undergoes racemization and isomerization to produce several types of CTX [… measurement
was performed based on highly specific monoclonal antibodies against amino acid sequence

Current use of bone turnover markers in the management of osteoporosis

JP Brown, A Don-Wauchope, P Douville, C Albert… - Clinical …, 2022 - Elsevier
… of bone collagen molecules (N- [NTX] and C-telopeptide … assays using of two antibodies to
the same amino acid sequence … β isomerization occurs in bone tissue in vivo with aging and is …

Measurement and clinical utility of βCTX in serum and plasma

SAP Chubb, SD Vasikaran - Advances in Clinical Chemistry, 2017 - Elsevier
… CTX sequence to isomerize over time to form a β-amino acid … This assay was shown to be
reactive to the eight amino acid … The use of two antibodies to the same amino acid sequence

Analytical considerations and plans to standardize or harmonize assays for the reference bone turnover markers PINP and β-CTX in blood

HP Bhattoa, E Cavalier, R Eastell, AC Heijboer… - Clinica Chimica …, 2021 - Elsevier
… and released during bone formation, and the C-telopeptide (β-… The anti-PINP antibodies
recognize two molecular forms of … available assays for the measurement of serum PINP. Table 1 …

Advances in bone turnover markers

L Di Medio, ML Brandi - Advances in Clinical Chemistry, 2021 - Elsevier
… -linking region in the C-telopeptide region is the carboxy-… from the newly synthesized form
(αCTX) to an isomerized form (βCTX). … antibodies directed against sclerostin decreased bone